A new biodegradable modified PVA/AZP and PCL composite scaffold for bone repair

Abstract The regeneration and repair of bone defects require implanting artificial materials with excellent mechanical biological properties similar to human bones. However, the compressive strength bioactivities 3D printing biodegradable like PVA are usually not enough for weight-bearing defect repair. In this study, we added AZP (amorphous zinc phosphate) nanoparticles increase scaffolds filled PCL into improve properties. Our results revealed that size was about 63.5 ± 29.3 nm, PVA/AZP scaffold printed a pore 600 μm. cell experiments showed compounded can effectively promote proliferation. Therefore, have good biocompatibility, has prospect application in tissue engineering.